Association of Genetic Variants With Warfarin-Associated Bleeding Among Patients of African Descent | Zendy

Tanima De | Zendy; Cristina Alarcón | Zendy; Wenndy Hernandez | Zendy; Ina Liko | Zendy; Larisa H. Cavallari | Zendy; Julio D. Duarte | Zendy; Minoli A. Perera | Zendy

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Association of Genetic Variants With Warfarin-Associated Bleeding Among Patients of African Descent

Author(s) -

Tanima De,

Cristina Alarcón,

Wenndy Hernandez,

Ina Liko,

Larisa H. Cavallari,

Julio D. Duarte,

Minoli A. Perera

Publication year - 2018

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2018.14955

Subject(s) - medicine , warfarin , cohort , odds ratio , population stratification , cohort study , population , logistic regression , adverse effect , single nucleotide polymorphism , genetics , genotype , gene , atrial fibrillation , biology , environmental health

Major warfarin-related bleeding occurs more frequently in African Americans than in other populations. Identification of potential genetic factors related to this adverse event may help identify at-risk patients.

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