Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases | Zendy

Paul D. Brown | Zendy; Kurt A. Jaeckle | Zendy; Karla V. Ballman | Zendy; Elana Farace | Zendy; Jane H. Cerhan | Zendy; S. Keith Anderson | Zendy; Xiomara W. Carrero | Zendy; Fred G. Barker | Zendy; Richard L. Deming | Zendy; Stuart H. Burri | Zendy; Cynthia Ménard | Zendy; Caroline Chung | Zendy; Volker W. Stieber | Zendy; Bruce E. Pollock | Zendy; Evanthia Galanis | Zendy; Jan C. Buckner | Zendy; Anthony L. Asher | Zendy

Open Access

Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases

Author(s) -

Paul D. Brown,

Kurt A. Jaeckle,

Karla V. Ballman,

Elana Farace,

Jane H. Cerhan,

S. Keith Anderson,

Xiomara W. Carrero,

Fred G. Barker,

Richard L. Deming,

Stuart H. Burri,

Cynthia Ménard,

Caroline Chung,

Volker W. Stieber,

Bruce E. Pollock,

Evanthia Galanis,

Jan C. Buckner,

Anthony L. Asher

Publication year - 2016

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2016.9839

Subject(s) - medicine , radiosurgery , quality of life (healthcare) , randomized controlled trial , cognition , radiation therapy , clinical endpoint , cognitive decline , dementia , disease , nursing , psychiatry

Whole brain radiotherapy (WBRT) significantly improves tumor control in the brain after stereotactic radiosurgery (SRS), yet because of its association with cognitive decline, its role in the treatment of patients with brain metastases remains controversial.

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