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Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism
Author(s) -
Geoffrey A. Block,
David A. Bushinsky,
Sunfa Cheng,
John Cunningham,
Bastian Dehmel,
Tilman B. Drüeke,
Markus Ketteler,
Reshma Kewalramani,
Kévin Martin,
Sharon M. Moe,
Uptal D. Patel,
Justin Silver,
Yan Sun,
Hao Wang,
Glenn M. Chertow
Publication year - 2017
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2016.19468
Subject(s) - cinacalcet , medicine , calcimimetic , placebo , secondary hyperparathyroidism , parathyroid hormone , urology , hemodialysis , adverse effect , hyperparathyroidism , alternative medicine , pathology , calcium
Secondary hyperparathyroidism contributes to extraskeletal calcification and is associated with all-cause and cardiovascular mortality. Control is suboptimal in the majority of patients receiving hemodialysis. An intravenously (IV) administered calcimimetic could improve adherence and reduce adverse gastrointestinal effects.

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