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Effect of Pritelivir Compared With Valacyclovir on Genital HSV-2 Shedding in Patients With Frequent Recurrences
Author(s) -
Anna Wald,
Burkhard Timmler,
Amalia Magaret,
Terri Warren,
Stephen K. Tyring,
Christine Johnston,
Kenneth H. Fife,
Stacy Selke,
MeeiLi Huang,
Hans-Peter Stobernack,
Holger Zimmermann,
Lawrence Corey,
Alexander Birkmann,
Helga RuebsamenSchaeff
Publication year - 2016
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2016.18189
Subject(s) - medicine , viral shedding , sex organ , herpes simplex virus , randomized controlled trial , valaciclovir , herpes genitalis , clinical trial , immunology , genital herpes , virus , viral disease , herpesviridae , genetics , biology
Current therapy of herpes infections relies on nucleoside analogues. Pritelivir is a well-tolerated novel herpes simplex virus (HSV) helicase-primase inhibitor that reduced genital shedding and lesions.

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