Effect of Acetazolamide vs Placebo on Duration of Invasive Mechanical Ventilation Among Patients With Chronic Obstructive Pulmonary Disease | Zendy

Christophe Faisy | Zendy; Ferhat Meziani | Zendy; Benjamin Planquette | Zendy; M. Clavel | Zendy; Arnaud Gacouin | Zendy; Caroline Bornstain | Zendy; Francis Schneider | Zendy; Alexandre Duguet | Zendy; Sébastien Gibot | Zendy; Nicolas Lerolle | Zendy; Jean-Damien Ricard | Zendy; Olivier Sanchez | Zendy; Michel Djibré | Zendy; J.-L. Ricôme | Zendy; Antoine Rabbat | Zendy; Nicholas Heming | Zendy; Saı̈k Urien | Zendy; Maxime Esvan | Zendy; Sandrine Katsahian | Zendy

Open Access

Effect of Acetazolamide vs Placebo on Duration of Invasive Mechanical Ventilation Among Patients With Chronic Obstructive Pulmonary Disease

Author(s) -

Christophe Faisy,

Ferhat Meziani,

Benjamin Planquette,

M. Clavel,

Arnaud Gacouin,

Caroline Bornstain,

Francis Schneider,

Alexandre Duguet,

Sébastien Gibot,

Nicolas Lerolle,

Jean-Damien Ricard,

Olivier Sanchez,

Michel Djibré,

J.-L. Ricôme,

Antoine Rabbat,

Nicholas Heming,

Saı̈k Urien,

Maxime Esvan,

Sandrine Katsahian

Publication year - 2016

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2016.0019

Subject(s) - medicine , acetazolamide , mechanical ventilation , copd , anesthesia , placebo , randomized controlled trial , metabolic alkalosis , intensive care unit , intubation , alkalosis , ventilation (architecture) , surgery , acidosis , mechanical engineering , engineering , alternative medicine , pathology

Acetazolamide has been used for decades as a respiratory stimulant for patients with chronic obstructive pulmonary disease (COPD) and metabolic alkalosis, but no large randomized placebo-controlled trial is available to confirm this approach.

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