Use of Phosphodiesterase Type 5 Inhibitors for Erectile Dysfunction and Risk of Malignant Melanoma
Author(s) -
Stacy Loeb,
Yasin Folkvaljon,
Mats Lambe,
David Robinson,
Hans Garmo,
Christian Ingvar,
Pär Stattin
Publication year - 2015
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2015.6604
Subject(s) - medicine , vardenafil , medical prescription , melanoma , tadalafil , erectile dysfunction , sildenafil , cgmp specific phosphodiesterase type 5 , population , relative risk , cancer , oncology , pharmacology , confidence interval , cancer research , environmental health
The target for the oral erectile dysfunction drugs, phosphodiesterase type 5 (PDE5) inhibitors, is part of a pathway implicated in the development of malignant melanoma. An increased risk of melanoma in sildenafil users was recently reported.
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