Association of Varying Number of Doses of Quadrivalent Human Papillomavirus Vaccine With Incidence of Condyloma
Author(s) -
Eva Herweijer,
Amy Levál,
Alexander Ploner,
Sandra Eloranta,
Julia F. Simard,
Joakim Dillner,
Eva Netterlid,
Pär Sparén,
Lisen ArnheimDahlström
Publication year - 2014
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2014.95
Subject(s) - medicine , vaccination , poisson regression , incidence (geometry) , cervical cancer , population , cohort , hpv vaccines , hpv infection , demography , pediatrics , immunology , cancer , environmental health , physics , sociology , optics
Determining vaccine dose-level protection is essential to minimize program costs and increase mass vaccination program feasibility. Currently, a 3-dose vaccination schedule is recommended for both the quadrivalent and bivalent human papillomavirus (HPV) vaccines. Although the primary goal of HPV vaccination programs is to prevent cervical cancer, condyloma related to HPV types 6 and 11 is also prevented with the quadrivalent vaccine and represents the earliest measurable preventable disease outcome for the HPV vaccine.
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