Association of Azithromycin With Mortality and Cardiovascular Events Among Older Patients Hospitalized With Pneumonia
Author(s) -
Eric M. Mortensen,
Ethan A. Halm,
Mary Jo Pugh,
Laurel A. Copeland,
Mark L. Metersky,
Michael J. Fine,
Christopher S. Johnson,
Carlos Álvarez,
Christopher R. Frei,
Chester B. Good,
Marcos I. Restrepo,
John R. Downs,
Antonio Anzueto
Publication year - 2014
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2014.4304
Subject(s) - medicine , azithromycin , pneumonia , propensity score matching , veterans affairs , odds ratio , retrospective cohort study , myocardial infarction , community acquired pneumonia , confounding , guideline , intensive care medicine , antibiotics , biology , pathology , microbiology and biotechnology
Although clinical practice guidelines recommend combination therapy with macrolides, including azithromycin, as first-line therapy for patients hospitalized with pneumonia, recent research suggests that azithromycin may be associated with increased cardiovascular events.
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