Association of Hydroxyethyl Starch Administration With Mortality and Acute Kidney Injury in Critically Ill Patients Requiring Volume Resuscitation | Zendy

Ryan Zarychanski | Zendy; Ahmed M Abou-Setta | Zendy; Alexis F. Turgeon | Zendy; Brett L. Houston | Zendy; Lauralyn McIntyre | Zendy; John C. Marshall | Zendy; Dean Fergusson | Zendy

Open Access

Association of Hydroxyethyl Starch Administration With Mortality and Acute Kidney Injury in Critically Ill Patients Requiring Volume Resuscitation

Author(s) -

Ryan Zarychanski,

Ahmed M Abou-Setta,

Alexis F. Turgeon,

Brett L. Houston,

Lauralyn McIntyre,

John C. Marshall,

Dean Fergusson

Publication year - 2013

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2013.430

Subject(s) - hydroxyethyl starch , medicine , acute kidney injury , resuscitation , randomized controlled trial , clinical trial , intensive care medicine , relative risk , population , emergency medicine , anesthesia , confidence interval , environmental health

Hydroxyethyl starch is commonly used for volume resuscitation yet has been associated with serious adverse events, including acute kidney injury and death. Clinical trials of hydroxyethyl starch are conflicting. Moreover, multiple trials from one investigator have been retracted because of scientific misconduct.

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