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Effect of High-Dose vs Standard-Dose Multivitamin Supplementation at the Initiation of HAART on HIV Disease Progression and Mortality in Tanzania
Author(s) -
Sheila Isanaka,
Ferdinand Mugusi,
Claudia Hawkins,
Donna Spiegelman,
James Okuma,
Said Aboud,
Chalamilla Guerino,
Wafaie W. Fawzi
Publication year - 2012
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2012.13083
Subject(s) - medicine , multivitamin , tanzania , human immunodeficiency virus (hiv) , disease , immunology , vitamin , environmental science , environmental planning
Large randomized trials have previously shown that high-dose micronutrient supplementation can increase CD4 counts and reduce human immunodeficiency virus (HIV) disease progression and mortality among individuals not receiving highly active antiretroviral therapy (HAART); however, the safety and efficacy of such supplementation has not been established in the context of HAART.

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