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Fibroblast Growth Factor 23 and Risks of Mortality and End-Stage Renal Disease in Patients With Chronic Kidney Disease
Author(s) -
Tamara Isakova,
Huiliang Xie,
Wei Yang,
Dawei Xie,
Amanda H. Anderson,
Julia J. Scialla,
Patricia Wahl,
Orlando M. Gutiérrez,
Susan Steigerwalt,
Jiang He,
Stanley A. Schwartz,
Joan C. Lo,
Akinlolu Ojo,
James Sondheimer,
Chiyuan Hsu,
James P. Lash,
Mary B. Leonard,
John W. Kusek,
Harold I. Feldman,
Myles Wolf
Publication year - 2011
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2011.826
Subject(s) - medicine , interquartile range , kidney disease , hazard ratio , fibroblast growth factor 23 , renal function , end stage renal disease , quartile , population , risk factor , prospective cohort study , proportional hazards model , confidence interval , gastroenterology , disease , parathyroid hormone , environmental health , calcium
A high level of the phosphate-regulating hormone fibroblast growth factor 23 (FGF-23) is associated with mortality in patients with end-stage renal disease, but little is known about its relationship with adverse outcomes in the much larger population of patients with earlier stages of chronic kidney disease.

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