Dried Blood Spot Real-time Polymerase Chain Reaction Assays to Screen Newborns for Congenital Cytomegalovirus Infection | Zendy

Suresh B. Boppana | Zendy

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Dried Blood Spot Real-time Polymerase Chain Reaction Assays to Screen Newborns for Congenital Cytomegalovirus Infection

Author(s) -

Suresh B. Boppana

Publication year - 2010

Publication title -

jama

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.688

H-Index - 680

eISSN - 1538-3598

pISSN - 0098-7484

DOI - 10.1001/jama.2010.423

Subject(s) - medicine , saliva , polymerase chain reaction , dried blood spot , primer (cosmetics) , cytomegalovirus , real time polymerase chain reaction , dried blood , newborn screening , virology , betaherpesvirinae , immunology , pediatrics , viral disease , herpesviridae , virus , biology , genetics , chemistry , organic chemistry , gene , chromatography

Reliable methods to screen newborns for congenital cytomegalovirus (CMV) infection are needed for identification of infants at increased risk of hearing loss. Since dried blood spots (DBS) are routinely collected for metabolic screening from all newborns in the United States, there has been interest in using DBS polymerase chain reaction (PCR)-based methods for newborn CMV screening.

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