Risk of Adverse Outcomes Associated With Concomitant Use of Clopidogrel and Proton Pump Inhibitors Following Acute Coronary Syndrome
Author(s) -
P. Michael Ho
Publication year - 2009
Publication title -
jama
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.688
H-Index - 680
eISSN - 1538-3598
pISSN - 0098-7484
DOI - 10.1001/jama.2009.261
Subject(s) - clopidogrel , medicine , acute coronary syndrome , hazard ratio , odds ratio , retrospective cohort study , confidence interval , concomitant , cardiology , myocardial infarction
Prior mechanistic studies reported that omeprazole decreases the platelet inhibitory effects of clopidogrel, yet the clinical significance of these findings is not clear.
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