Parental Posttraumatic Stress Disorder as a Vulnerability Factor for Low Cortisol Trait in Offspring of Holocaust Survivors
Author(s) -
Rachel Yehuda,
Martin H. Teicher,
Jonathan R. Seckl,
Robert Grossman,
Adam Morris,
Linda M. Bierer
Publication year - 2007
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.64.9.1040
Subject(s) - offspring , psychology , circadian rhythm , hydrocortisone , medicine , basal (medicine) , clinical psychology , endocrinology , physiology , developmental psychology , pregnancy , biology , genetics , insulin
Lower cortisol levels in posttraumatic stress disorder (PTSD) may reflect a preexisting vulnerability associated with developing the disorder after trauma exposure. Because offspring of trauma survivors with PTSD have a greater prevalence of PTSD after their own life events than offspring of trauma survivors without PTSD and offspring of nonexposed persons, examination of patterns of basal cortisol secretion in such offspring provides an opportunity to test this hypothesis.
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