Stress-Related Negative Affectivity and Genetically Altered Serotonin Transporter Function
Author(s) -
Nele Jacobs,
Günter Kenis,
Frenk Peeters,
Cathérine Derom,
Robert Vlietinck,
Jim van Os
Publication year - 2006
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.63.9.989
Subject(s) - neuroticism , 5 httlpr , negative affectivity , psychology , moderation , serotonin transporter , depression (economics) , population , dysfunctional family , clinical psychology , developmental psychology , psychiatry , personality , medicine , serotonin , anxiety , social psychology , receptor , environmental health , economics , macroeconomics
Genetic moderation of the depression-inducing effects of stressful life events (SLEs) has been reported, but findings suggest that genes may not moderate the effects of SLEs per se but instead may moderate the risk of depression associated with the stable tendency to develop negative emotions in response to minor environmental experiences.
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