Cigarette Smoking Saturates Brain α4β2 Nicotinic Acetylcholine Receptors | Zendy

Arthur L. Brody | Zendy; M. Mandelkern | Zendy; Edythe D. London | Zendy; Richard Olmstead | Zendy; Judah Farahi | Zendy; David Scheibal | Zendy; Jennifer Jou | Zendy; Valerie Allen | Zendy; Emmanuelle Tiongson | Zendy; Svetlana I. Chefer | Zendy; Andrei O. Koren | Zendy; Alexey G. Mukhin | Zendy

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Cigarette Smoking Saturates Brain α4β2 Nicotinic Acetylcholine Receptors

Author(s) -

Arthur L. Brody,

M. Mandelkern,

Edythe D. London,

Richard Olmstead,

Judah Farahi,

David Scheibal,

Jennifer Jou,

Valerie Allen,

Emmanuelle Tiongson,

Svetlana I. Chefer,

Andrei O. Koren,

Alexey G. Mukhin

Publication year - 2006

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.63.8.907

Subject(s) - nicotine , radioligand , nicotinic agonist , varenicline , alpha (finance) , beta (programming language) , smoking cessation , acetylcholine receptor , craving , pharmacology , medicine , chemistry , receptor , endocrinology , anesthesia , nuclear medicine , addiction , psychiatry , pathology , surgery , construct validity , computer science , patient satisfaction , programming language

2-[18F]fluoro-3-(2(S)-azetidinylmethoxy) pyridine (2-F-A-85380, abbreviated as 2-FA) is a recently developed radioligand that allows for visualization of brain alpha 4 beta 2* nicotinic acetylcholine receptors (nAChRs) with positron emission tomography (PET) scanning in humans.

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