Reduced Muscarinic Type 2 Receptor Binding in Subjects With Bipolar Disorder
Author(s) -
Dara M. Can,
Richard E. Carson,
Allison C. Nugent,
William C. Eckelman,
Dale O. Kiesewetter,
Joan P. Williams,
Denise Rollis,
Michele Drevets,
Shilpa K Gandhi,
Gerardo Solorio,
Wayne C. Drevets
Publication year - 2006
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.63.7.741
Subject(s) - bipolar disorder , psychology , medicine , major depressive disorder , bipolar ii disorder , depression (economics) , endocrinology , psychiatry , amygdala , mood , economics , macroeconomics
A variety of indirect evidence has implicated the central muscarinic-cholinergic system, and more specifically the type 2 muscarinic (M2) receptor, in the pathogenesis of depressive symptoms arising in major depressive disorder and bipolar disorder.
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