Neural Correlates of Antinociception in Borderline Personality Disorder | Zendy

Christian Schmahl | Zendy; Martin Bohus | Zendy; Fabrizio Esposito | Zendy; RolfDetlef Treede | Zendy; Francesco Di Salle | Zendy; Wolfgang Greffrath | Zendy; Petra Ludaescher | Zendy; Anja Jochims | Zendy; Klaus Lieb | Zendy; Klaus Scheffler | Zendy; Jürgen Hennig | Zendy; Erich Seifritz | Zendy

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Neural Correlates of Antinociception in Borderline Personality Disorder

Author(s) -

Christian Schmahl,

Martin Bohus,

Fabrizio Esposito,

RolfDetlef Treede,

Francesco Di Salle,

Wolfgang Greffrath,

Petra Ludaescher,

Anja Jochims,

Klaus Lieb,

Klaus Scheffler,

Jürgen Hennig,

Erich Seifritz

Publication year - 2006

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.63.6.659

Subject(s) - anterior cingulate cortex , psychology , functional magnetic resonance imaging , dorsolateral prefrontal cortex , borderline personality disorder , prefrontal cortex , amygdala , nociception , cingulate cortex , audiology , brain activity and meditation , blood oxygen level dependent , neuroscience , medicine , cognition , electroencephalography , psychiatry , central nervous system , receptor

A characteristic feature of borderline personality disorder (BPD) is self-injurious behavior in conjunction with stress-induced reduction of pain perception. Reduced pain sensitivity has been experimentally confirmed in patients with BPD, but the neural correlates of antinociceptive mechanisms in BPD are unknown. We predicted that heat stimuli in patients with BPD would activate brain areas concerned with cognitive and emotional evaluation of pain.

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