Open AccessStress-Induced Cocaine Craving and Hypothalamic-Pituitary-Adrenal Responses Are Predictive of Cocaine Relapse Outcomes
Author(s) -
Rajita Sinha,
Miguel García,
Prashni Paliwal,
Mary Jeanne Kreek,
Bruce J. Rounsaville
Publication year - 2006
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.63.3.324
Subject(s) - craving , cocaine dependence , psychology , hypothalamic–pituitary–adrenal axis , cocaine use , medicine , arousal , heroin , psychiatry , drug , clinical psychology , addiction , hormone , neuroscience
Cocaine dependence is associated with high rates of relapse. Stress and drug cue exposure are known to increase cocaine craving and stress arousal, but the association between these responses and cocaine relapse has not been previously studied.
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