Augmentation of Exposure Therapy With D-Cycloserine for Social Anxiety Disorder | Zendy

Stefan G. Hofmann | Zendy; Alicia E. Meuret | Zendy; Jasper A. J. Smits | Zendy; Naomi M. Simon | Zendy; Mark H. Pollack | Zendy; Katherine Eisenmenger | Zendy; Michael Shiekh | Zendy; Michael W. Otto | Zendy

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Augmentation of Exposure Therapy With D-Cycloserine for Social Anxiety Disorder

Author(s) -

Stefan G. Hofmann,

Alicia E. Meuret,

Jasper A. J. Smits,

Naomi M. Simon,

Mark H. Pollack,

Katherine Eisenmenger,

Michael Shiekh,

Michael W. Otto

Publication year - 2006

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.63.3.298

Subject(s) - exposure therapy , placebo , anxiety , social anxiety , psychology , clinical psychology , randomized controlled trial , randomization , generalized anxiety disorder , psychiatry , medicine , alternative medicine , pathology

Social anxiety disorder (SAD) is common and debilitating. Although exposure therapy is one of the most effective forms of psychotherapy for this disorder, many patients remain symptomatic. Fear reduction in exposure therapy is similar to extinction learning, and early clinical data with specific phobias suggest that the treatment effects of exposure therapy for SAD may be enhanced with d-cycloserine, an agonist at the glutamatergic N-methyl-d-aspartate receptor.

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