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Familial Aggregation of Eye-Tracking Endophenotypes in Families of Schizophrenic Patients
Author(s) -
L. Elliot Hong,
Braxton D. Mitchell,
Matthew T. Avila,
Helene Adami,
Robert P. McMahon,
Gunvant K. Thaker
Publication year - 2006
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.63.3.259
Subject(s) - heritability , endophenotype , sibling , intraclass correlation , smooth pursuit , schizophrenia (object oriented programming) , family aggregation , psychology , medicine , psychiatry , clinical psychology , psychometrics , developmental psychology , genetics , biology , cognition , eye movement , disease , neuroscience
Abnormal smooth pursuit eye movements (SPEMs) are some of the most reproducible biological changes associated with the susceptibility for schizophrenia. Recent studies have suggested that deficit in predictive pursuit, a specific component of the SPEMs, marks schizophrenia susceptibility.

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