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Injectable, Sustained-Release Naltrexone for the Treatment of Opioid Dependence
Author(s) -
Sandra D. Comer,
Maria A. Sullivan,
Elmer Yu,
Jami L. Rothenberg,
Herbert D. Kleber,
Kyle Kampman,
Charles A. Dackis,
Charles P. O’Brien
Publication year - 2006
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.63.2.210
Subject(s) - naltrexone , placebo , heroin , methadone , opioid , medicine , urine , anesthesia , narcotic antagonist , opioid antagonist , randomized controlled trial , pharmacology , (+) naloxone , drug , alternative medicine , receptor , pathology
Oral naltrexone can completely antagonize the effects produced by opioid agonists. However, poor compliance with naltrexone has been a major obstacle to the effective treatment of opioid dependence.

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