Open AccessPregabalin for Treatment of Generalized Anxiety Disorder
Author(s) -
Karl Rickels,
Mark H. Pollack,
Douglas E. Feltner,
R. Bruce Lydiard,
Daniel L. Zimbroff,
Robert J. Bielski,
Kathy Tobias,
Jerri Brock,
Gwen L. Zornberg,
Atul C. Pande
Publication year - 2005
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.62.9.1022
Subject(s) - pregabalin , alprazolam , placebo , anxiolytic , generalized anxiety disorder , anxiety , hamilton anxiety rating scale , anesthesia , psychology , medicine , anticonvulsant , psychiatry , epilepsy , alternative medicine , pathology
Pregabalin inhibits release of excess excitatory neurotransmitters, presumably by binding to the alpha2-delta subunit protein of widely distributed voltage-dependent calcium channels in the brain and spinal cord.
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