The Interaction of Stressful Life Events and a Serotonin Transporter Polymorphism in the Prediction of Episodes of Major Depression
Author(s) -
Kenneth S. Kendler,
Jonathan W. Kuhn,
Jen Vittum,
Carol A. Prescott,
Brien P. Riley
Publication year - 2005
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.62.5.529
Subject(s) - serotonin transporter , 5 httlpr , psychology , anxiety , depression (economics) , genotype , moderation , allele , population , twin study , clinical psychology , psychiatry , medicine , biology , genetics , gene , heritability , social psychology , macroeconomics , economics , environmental health
Prior evidence from twin studies suggested genetic moderation of the depressogenic effects of stressful life events (SLEs). Can the specific genes involved in this effect be identified?
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom