Regionally Specific Disturbance of Dorsolateral Prefrontal–Hippocampal Functional Connectivity in Schizophrenia
Author(s) -
Andreas MeyerLindenberg,
Rosanna K. Olsen,
Philip D. Kohn,
Timothy T. Brown,
Michael Egan,
Daniel R. Weinberger,
Karen F. Berman
Publication year - 2005
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.62.4.379
Subject(s) - dorsolateral prefrontal cortex , working memory , psychology , schizophrenia (object oriented programming) , neuroscience , prefrontal cortex , neuroimaging , hippocampal formation , cerebellum , abnormality , cognition , psychiatry
Two brain regions often implicated in schizophrenia are the dorsolateral prefrontal cortex (DLPFC) and the hippocampal formation (HF). It has been hypothesized that the pathophysiology of the disorder might involve an alteration of functional interactions between medial temporal and prefrontal areas.
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