Antipsychotic Drug Effects on Brain Morphology in First-Episode Psychosis | Zendy

Jeffrey A. Lieberman | Zendy

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Antipsychotic Drug Effects on Brain Morphology in First-Episode Psychosis

Author(s) -

Jeffrey A. Lieberman

Publication year - 2005

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.62.4.361

Subject(s) - haloperidol , olanzapine , neurocognitive , antipsychotic , psychology , psychosis , magnetic resonance imaging , medicine , brain morphometry , psychopathology , psychiatry , schizophrenia (object oriented programming) , radiology , cognition , dopamine

Pathomorphologic brain changes occurring as early as first-episode schizophrenia have been extensively described. Longitudinal studies have demonstrated that these changes may be progressive and associated with clinical outcome. This raises the possibility that antipsychotics might alter such pathomorphologic progression in early-stage schizophrenia.

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