Functional Neuroanatomical Substrates of Altered Reward Processing in Major Depressive Disorder Revealed by a Dopaminergic Probe | Zendy

Lescia K. Tremblay | Zendy; Claudio A. Naranjo | Zendy; Simon J. Graham | Zendy; Nathan Herrmann | Zendy; Helen S. Mayberg | Zendy; Stephanie J. Hevenor | Zendy; Usoa E. Busto | Zendy

Open Access

Functional Neuroanatomical Substrates of Altered Reward Processing in Major Depressive Disorder Revealed by a Dopaminergic Probe

Author(s) -

Lescia K. Tremblay,

Claudio A. Naranjo,

Simon J. Graham,

Nathan Herrmann,

Helen S. Mayberg,

Stephanie J. Hevenor,

Usoa E. Busto

Publication year - 2005

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.62.11.1228

Subject(s) - major depressive disorder , functional magnetic resonance imaging , psychology , dopaminergic , orbitofrontal cortex , dextroamphetamine , prefrontal cortex , ventral striatum , putamen , neuroscience , dopamine , medicine , striatum , amphetamine , amygdala , cognition

The pathophysiology of major depressive disorder (MDD) includes disturbances in several neuroanatomical substrates and neurotransmitter systems. The challenge is to elucidate the brain mechanisms of MDD behavioral symptoms, chiefly those of anhedonia.

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