Anomalous Prefrontal-Subcortical Activation in Familial Pediatric BipolarDisorder | Zendy

Kiki D. Chang | Zendy; Nancy E. Adleman | Zendy; Kimberly Dienes | Zendy; Diana I. Simeonova | Zendy; Vinod Me | Zendy; Allan L. Reiss | Zendy

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Anomalous Prefrontal-Subcortical Activation in Familial Pediatric BipolarDisorder

Author(s) -

Kiki D. Chang,

Nancy E. Adleman,

Kimberly Dienes,

Diana I. Simeonova,

Vinod Me,

Allan L. Reiss

Publication year - 2004

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.61.8.781

Subject(s) - functional magnetic resonance imaging , dorsolateral prefrontal cortex , psychology , bipolar disorder , insula , audiology , working memory , anterior cingulate cortex , neuroimaging , supplementary motor area , prefrontal cortex , putamen , functional neuroimaging , neuroscience , thalamus , medicine , cognition

The neurobiological features of pediatric bipolar disorder (BD) are largely unknown. Children and adolescents with BD may be important to study with functional neuroimaging techniques because of their unique status of early-onset BD and high familial loading for the disorder. Neuroimaging studies of adults with BD have implicated the dorsolateral prefrontal cortex (DLPFC) and anterior cingulate cortex (ACC) in the development of this disorder.

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