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A Family Study of Alcohol Dependence
Author(s) -
John I. Nürnberger,
Ryan E. Wiegand,
Kathleen K. Bucholz,
Sean O’Connor,
Eric T. Meyer,
Theodore Reich,
John P. Rice,
Marc A. Schuckit,
Lucy Jane King,
Theodore A. Petti,
Laura J. Bierut,
Anthony L. Hinrichs,
Samuel Kuperman,
Victor Hesselbrock,
Bernice Porjesz
Publication year - 2004
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.61.12.1246
Subject(s) - proband , alcohol dependence , psychiatry , family history , psychology , comorbidity , family aggregation , alcohol use disorder , panic disorder , antisocial personality disorder , minnesota multiphasic personality inventory , clinical psychology , substance dependence , substance abuse , medicine , personality , anxiety , poison control , alcohol , injury prevention , disease , medical emergency , genetics , chemistry , mutation , biology , social psychology , biochemistry , gene
Alcohol dependence tends to aggregate within families. We analyzed data from the family collection of the Collaborative Study on the Genetics of Alcoholism to quantify familial aggregation using several different criterion sets. We also assessed the aggregation of other psychiatric disorders in the same sample to identify areas of possible shared genetic vulnerability.

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