Rapid Switching of Mood in Families With Multiple Cases of Bipolar Disorder | Zendy

Dean F. MacKin | Zendy; Peter P. Zandi | Zendy; Elliot S. Gershon | Zendy; John I. Nürnberger | Zendy; Theodore Reich | Zendy; J. Raymond DePaulo | Zendy

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Rapid Switching of Mood in Families With Multiple Cases of Bipolar Disorder

Author(s) -

Dean F. MacKin,

Peter P. Zandi,

Elliot S. Gershon,

John I. Nürnberger,

Theodore Reich,

J. Raymond DePaulo

Publication year - 2003

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.60.9.921

Subject(s) - bipolar disorder , borderline personality disorder , comorbidity , psychology , mood , substance abuse , anxiety , clinical psychology , psychiatry , population , spectrum disorder , bipolar ii disorder , prevalence of mental disorders , mood disorders , mood swing , medicine , environmental health

Heterogeneity within the diagnostic construct of bipolar disorder is most likely an obstacle to discovering its causes. Phenomena in the bipolar spectrum, including rapid cycling, cyclothymia, and affective instability of borderline personality, may be important markers of etiologic heterogeneity. Rapid switching of mood may be central to these phenomena.

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