Decreased Thalamic Expression of the Homeobox Gene DLX1 in Psychosis | Zendy

Marjan Kromkamp | Zendy; H.B.M. Uylings | Zendy; Marten P. Smidt | Zendy; Anita J. C. G. M. Hellemons | Zendy; J. Peter H. Burbach | Zendy; René S. Kahn | Zendy

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Decreased Thalamic Expression of the Homeobox Gene DLX1 in Psychosis

Author(s) -

Marjan Kromkamp,

H.B.M. Uylings,

Marten P. Smidt,

Anita J. C. G. M. Hellemons,

J. Peter H. Burbach,

René S. Kahn

Publication year - 2003

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.60.9.869

Subject(s) - psychosis , schizophrenia (object oriented programming) , bipolar disorder , homeobox , family history , psychology , psychiatry , neuroscience , medicine , biology , gene expression , gene , genetics , cognition

A shared vulnerability to develop psychosis can be related to abnormalities in thalamic circuits in schizophrenia and bipolar disorder and could be a genetic link between these disorders. Homeobox genes involved in development and differentiation of the brain could play an important role in these disorders.

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