Progressive Decrease of Left Heschl Gyrus and Planum Temporale Gray Matter Volume in First-Episode Schizophrenia
Author(s) -
Kiyoto Kasai,
Martha E. Shenton,
Dean F. Salisbury,
Yoshio Hirayasu,
Toshiaki Onitsuka,
Magdalena H. Spencer,
Deborah YurgelunTodd,
Ron Kikinis,
Ferenc A. Jólesz,
Robert W. McCarley
Publication year - 2003
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.60.8.766
Subject(s) - planum temporale , psychology , psychosis , gyrus , audiology , superior temporal gyrus , schizophrenia (object oriented programming) , psychiatry , neuroscience , medicine , functional magnetic resonance imaging
The Heschl gyrus and planum temporale have crucial roles in auditory perception and language processing. Our previous investigation using magnetic resonance imaging (MRI) indicated smaller gray matter volumes bilaterally in the Heschl gyrus and in left planum temporale in patients with first-episode schizophrenia but not in patients with first-episode affective psychosis. We sought to determine whether there are progressive decreases in anatomically defined MRI gray matter volumes of the Heschl gyrus and planum temporale in patients with first-episode schizophrenia and also in patients with first-episode affective psychosis.
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