A Placebo-Controlled 18-Month Trial of Lamotrigine and Lithium Maintenance Treatment in Recently Manic or Hypomanic Patients With Bipolar I Disorder | Zendy

Charles L. Bowden | Zendy

Open Access

A Placebo-Controlled 18-Month Trial of Lamotrigine and Lithium Maintenance Treatment in Recently Manic or Hypomanic Patients With Bipolar I Disorder

Author(s) -

Charles L. Bowden

Publication year - 2003

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.60.4.392

Subject(s) - lamotrigine , placebo , mood stabilizer , bipolar disorder , tolerability , lithium (medication) , bipolar i disorder , psychology , mania , medicine , psychiatry , treatment of bipolar disorder , adverse effect , epilepsy , alternative medicine , pathology

Lamotrigine has been shown to be an effective treatment for bipolar depression and rapid cycling in placebo-controlled clinical trials. This double-blind, placebo-controlled study was conducted to assess the efficacy and tolerability of lamotrigine and lithium compared with placebo for the prevention of relapse or recurrence of mood episodes in recently manic or hypomanic patients with bipolar I disorder.

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