Regulation of Human Affective Responses by Anterior Cingulate and Limbic µ-Opioid Neurotransmission | Zendy

JonKar Zubieta | Zendy; Terence A. Ketter | Zendy; Joshua A. Bueller | Zendy; Yanjun Xu | Zendy; Michael R. Kilbourn | Zendy; Elizabeth A. Young | Zendy; Robert A. Koeppe | Zendy

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Regulation of Human Affective Responses by Anterior Cingulate and Limbic µ-Opioid Neurotransmission

Author(s) -

JonKar Zubieta,

Terence A. Ketter,

Joshua A. Bueller,

Yanjun Xu,

Michael R. Kilbourn,

Elizabeth A. Young,

Robert A. Koeppe

Publication year - 2003

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.60.11.1145

Subject(s) - anterior cingulate cortex , neuroscience , neurotransmission , psychology , neurochemical , amygdala , limbic system , ventral pallidum , opioid receptor , cingulate cortex , neurotransmitter , opioid , sadness , medicine , receptor , psychiatry , central nervous system , basal ganglia , cognition , globus pallidus , anger

Human affective responses appear to be regulated by limbic and paralimbic circuits. However, much less is known about the neurochemical systems engaged in this regulation. The mu-opioid neurotransmitter system is distributed in, and thought to regulate the function of, brain regions centrally implicated in affective processing.

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