White Matter Hyperintensity Progression and Late-Life Depression Outcomes
Author(s) -
Warren D. Taylor,
David C. Steffens,
James R. MacFall,
Douglas R. McQuoid,
Martha E. Payne,
James M. Provenzale,
K. Ranga Rama Krishnan
Publication year - 2003
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.60.11.1090
Subject(s) - hyperintensity , depression (economics) , psychology , magnetic resonance imaging , medicine , late life depression , antidepressant , major depressive disorder , cardiology , electroconvulsive therapy , rating scale , white matter , brain size , montgomery–åsberg depression rating scale , psychiatry , schizophrenia (object oriented programming) , cognition , radiology , developmental psychology , economics , macroeconomics , anxiety
White matter hyperintensities (WMHs) are bright foci seen in the parenchyma of the brain on T2-weighted cranial magnetic resonance imaging (MRI) scans and are associated with geriatric depression. Because they are associated with age, they should increase in number and size over time. To our knowledge, this is the first longitudinal, volumetric MRI study of WMHs in depression.
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