Gene Expression Profile for Schizophrenia
Author(s) -
Scott E. Hemby,
Stephen D. Ginsberg,
Brian P. Brunk,
Steven E. Arnold,
John Q. Trojanowski,
James Eberwine
Publication year - 2002
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.59.7.631
Subject(s) - biology , gene expression , synaptophysin , glutamate receptor , neuroscience , microbiology and biotechnology , receptor , gene , genetics , immunohistochemistry , immunology
Several lines of evidence indicate the altered function of the temporal lobe, including the hippocampus and entorhinal cortex (EC), is associated with schizophrenia. We used single-cell gene expression technologies to assess coordinate changes in the expression of multiple genes, including neuronal signaling and synaptic-related markers in EC layer II stellate neurons.
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