Blunted Prefrontal Cortical 18Fluorodeoxyglucose Positron Emission Tomography Response to Meta-Chlorophenylpiperazine in Impulsive Aggression
Author(s) -
Antonia S. New,
Erin A. Hazlett,
Monte S. Buchsbaum,
Marianne Goodman,
Diedre Reynolds,
Vivian Mitropoulou,
Larry Sprung,
Robert B. Shaw,
Harold Koenigsberg,
Jimcy Platholi,
Jeremy M. Silverman,
Larry J. Siever
Publication year - 2002
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.59.7.621
Subject(s) - anterior cingulate cortex , serotonergic , orbitofrontal cortex , psychology , aggression , neuroscience , prefrontal cortex , laterality , cingulate cortex , medicine , cognition , serotonin , developmental psychology , central nervous system , receptor
Impulsive aggression is a prevalent problem and yet little is known about its neurobiology. Preclinical and human studies suggest that the orbital frontal cortex and anterior cingulate cortex play an inhibitory role in the regulation of aggression.
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