Abnormalities in Glucose Regulation During Antipsychotic Treatment of Schizophrenia
Author(s) -
John W. Newcomer,
Dan Haupt,
Robert Fucetola,
Angela K. Melson,
Julia Schweiger,
Benjamin P. Cooper,
Gregg Selke
Publication year - 2002
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.59.4.337
Subject(s) - clozapine , risperidone , medicine , olanzapine , antipsychotic , schizophrenia (object oriented programming) , endocrinology , diabetes mellitus , population , atypical antipsychotic , insulin , psychiatry , environmental health
Hyperglycemia and type 2 diabetes mellitus are more common in schizophrenia than in the general population. Glucoregulatory abnormalities have also been associated with the use of antipsychotic medications themselves. While antipsychotics may increase adiposity, which can decrease insulin sensitivity, disease- and medication-related differences in glucose regulation might also occur independent of differences in adiposity.
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