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Previous studies suggest that the impact of early insults predisposing to schizophrenia may have differential consequences by sex. We hypothesized that brain regions found to be structurally different in normal men and women (sexual dimorphisms) and abnormal in schizophrenia would show significant sex differences in brain abnormalities, particularly in the cortex, in schizophrenia.

Impact of Normal Sexual Dimorphisms on Sex Differences in Structural Brain Abnormalities in Schizophrenia Assessed by Magnetic Resonance Imaging