Age-Related Changes in Frontal and Temporal Lobe Volumes in Men | Zendy

George Bartzokis | Zendy; Mace Beckson | Zendy; Po H. Lu | Zendy; Keith H. Nuechterlein | Zendy; Nancy Edwards | Zendy; Jim Mintz | Zendy

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Age-Related Changes in Frontal and Temporal Lobe Volumes in Men

Author(s) -

George Bartzokis,

Mace Beckson,

Po H. Lu,

Keith H. Nuechterlein,

Nancy Edwards,

Jim Mintz

Publication year - 2001

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.58.5.461

Subject(s) - white matter , frontal lobe , temporal lobe , magnetic resonance imaging , coronal plane , grey matter , brain size , psychology , anatomy , medicine , neuroscience , epilepsy , radiology

Imaging and postmortem studies provide converging evidence that, beginning in adolescence, gray matter volume declines linearly until old age, while cerebrospinal fluid volumes are stable in adulthood (age 20-50 years). Given the fixed volume of the cranium in adulthood, it is surprising that most studies observe no white matter volume expansion after approximately age 20 years. We examined the effects of the aging process on the frontal and temporal lobes.

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