Open AccessAdvancing Paternal Age and the Risk of Schizophrenia
Author(s) -
Dolores Malaspina,
Susan Harlap,
Shmuel Fennig,
D. Heiman,
Daniella Nahon,
Dina Feldman,
Ezra Susser
Publication year - 2001
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.58.4.361
Subject(s) - offspring , schizophrenia (object oriented programming) , population , confidence interval , confounding , demography , psychiatry , socioeconomic status , psychosis , psychology , medicine , pregnancy , genetics , biology , sociology
A major source of new mutations in humans is the male germ line, with mutation rates monotonically increasing as father's age at conception advances, possibly because of accumulating replication errors in spermatogonial cell lines.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom