Differential Circadian Rhythm Disturbances in Men with Alzheimer Disease and Frontotemporal Degeneration
Author(s) -
David G. Harper,
Edward G. Stopa,
Ann C. McKee,
Andrew Satlin,
Patricia Harlan,
Rachel Goldstein,
Ladislav Volicer
Publication year - 2001
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.58.4.353
Subject(s) - circadian rhythm , frontotemporal dementia , dementia , rhythm , psychology , lewy body , alzheimer's disease , medicine , dementia with lewy bodies , frontotemporal lobar degeneration , disease , cardiology
Caregiver exhaustion is a frequent consequence of sleep disturbance and rest-activity rhythm disruption that occurs in dementia. This exhaustion is the causal factor most frequently cited by caregivers in making the decision to institutionalize patients with dementia. Recent studies have implicated dysfunction of the circadian pacemaker in the etiology of these disturbances in dementia.
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