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Focal Gray Matter Density Changes in Schizophrenia
Author(s) -
Hilleke E. Hulshoff Pol,
Hugo G. Schnack,
René C.W. Mandl,
Neeltje E.M. van Haren,
Hilde Koning,
D. Louis Collins,
Alan C. Evans,
René S. Kahn
Publication year - 2001
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.58.12.1118
Subject(s) - schizophreniform disorder , psychology , amygdala , voxel based morphometry , putamen , globus pallidus , white matter , grey matter , magnetic resonance imaging , neuroscience , audiology , psychosis , basal ganglia , medicine , psychiatry , central nervous system , schizoaffective disorder , radiology
The view that schizophrenia is a brain disease particularly involving decrements in gray matter is supported by findings from many imaging studies. However, it is unknown whether the (progressive) loss of tissue affects the brain globally or whether tissue loss is more prominent in some areas than in others.

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