Serum Thyrotropin Concentrations and Bioactivity During Sleep Deprivation in Depression | Zendy

David N. Orth | Zendy; Richard C. Shelton | Zendy; Wendell E. Nicholson | Zendy; Paolo BeckPeccoz | Zendy; Andrew J. Tomarken | Zendy; Luca Persani | Zendy; Peter T. Loosen | Zendy

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Serum Thyrotropin Concentrations and Bioactivity During Sleep Deprivation in Depression

Author(s) -

David N. Orth,

Richard C. Shelton,

Wendell E. Nicholson,

Paolo BeckPeccoz,

Andrew J. Tomarken,

Luca Persani,

Peter T. Loosen

Publication year - 2001

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.58.1.77

Subject(s) - medicine , endocrinology , subclinical infection , thyroid function , sleep deprivation , depression (economics) , circadian rhythm , thyrotropin releasing hormone , trh stimulation test , thyroid , thyroid function tests , psychology , hormone , economics , macroeconomics

One night of sleep deprivation induces a brief remission in about half of depressed patients. Subclinical hypothyroidism may be associated with depression, and changes in hypothalamic-pituitary-thyroid function may affect the mood response to sleep deprivation. We wished to define precisely the status of the hypothalamic-pituitary-thyroid axis of depressed patients during sleep deprivation and the possible relationship of hypothalamic-pituitary-thyroid function to the mood response.

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