A Randomized, Placebo-Controlled 12-Month Trial of Divalproex and Lithium in Treatment of Outpatients With Bipolar I Disorder | Zendy

Charles L. Bowden | Zendy; Joseph R. Calabrese | Zendy; Susan L. McElroy | Zendy; László Gyulai | Zendy; Adel Wassef | Zendy; Frederick Petty | Zendy; Harrison G. Pope | Zendy; C. James Chou | Zendy; Paul E. Keck | Zendy; Linda Rhodes | Zendy; Alan C. Swann | Zendy; Robert M. A. Hirschfeld | Zendy; Patricia J. Wozniak | Zendy

Open Access

A Randomized, Placebo-Controlled 12-Month Trial of Divalproex and Lithium in Treatment of Outpatients With Bipolar I Disorder

Author(s) -

Charles L. Bowden,

Joseph R. Calabrese,

Susan L. McElroy,

László Gyulai,

Adel Wassef,

Frederick Petty,

Harrison G. Pope,

C. James Chou,

Paul E. Keck,

Linda Rhodes,

Alan C. Swann,

Robert M. A. Hirschfeld,

Patricia J. Wozniak

Publication year - 2000

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.57.5.481

Subject(s) - divalproex , bipolar disorder , placebo , mania , mood stabilizer , psychology , mood , psychiatry , randomized controlled trial , discontinuation , randomization , bipolar i disorder , lithium (medication) , medicine , pediatrics , alternative medicine , pathology

Long-term outcomes are often poor in patients with bipolar disorder despite treatment; more effective treatments are needed to reduce recurrences and morbidity. This study compared the efficacy of divalproex, lithium, and placebo as prophylactic therapy.

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