Structural Abnormalities of Subicular Dendrites in Subjects With Schizophrenia and Mood Disorders | Zendy

Gorazd Rosoklija | Zendy; Glen Toomayan | Zendy; Steven P. Ellis | Zendy; John G. Keilp | Zendy; J. John Mann | Zendy; Norman Latov | Zendy; Arthur P. Hays | Zendy; Andrew J. Dwork | Zendy

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Structural Abnormalities of Subicular Dendrites in Subjects With Schizophrenia and Mood Disorders

Author(s) -

Gorazd Rosoklija,

Glen Toomayan,

Steven P. Ellis,

John G. Keilp,

J. John Mann,

Norman Latov,

Arthur P. Hays,

Andrew J. Dwork

Publication year - 2000

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.57.4.349

Subject(s) - subiculum , schizophrenia (object oriented programming) , neuroscience , mood disorders , psychology , psychosis , dendritic spine , hippocampus , psychiatry , hippocampal formation , anxiety , dentate gyrus

Postmortem studies of the subiculum from subjects with schizophrenia have detected smaller pyramidal cell bodies and diminished immunoreactivity for the dendritic protein, microtubule-associated protein 2. While these findings suggest that subicular pyramidal cell dendrites may be structurally altered in subjects with schizophrenia, this possibility had not been tested directly.

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