Open AccessStress-Related Changes in Proinflammatory Cytokine Production in Wounds
Author(s) -
Ronald Glaser,
Janice K. Kiecolt-Glaser,
Phillip T. Marucha,
Robert C. MacCallum,
Bryon Laskowski,
W B Malarkey
Publication year - 1999
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.56.5.450
Subject(s) - proinflammatory cytokine , cytokine , wound healing , medicine , inflammation , suction blister , interleukin 6 , immune system , immunology , surgery
Several recent studies have shown that stress markedly delays wound healing. This study assessed the relationship between psychological stress and the secretion of proinflammatory cytokines at an actual wound site, providing in vivo data on the development of local immune responses that are central in the early stages of wound repair.
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