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Frontal Brain Asymmetry as a Biological Substrate of Emotions in Patients With Panic Disorders
Author(s) -
Georg Wiedemann,
Paul Pauli,
Wilhelm Dengler,
W. Lutzenberger,
Niels Birbaumer,
Gerhard Buchkremer
Publication year - 1999
Publication title -
archives of general psychiatry
Language(s) - English
Resource type - Journals
eISSN - 1538-3636
pISSN - 0003-990X
DOI - 10.1001/archpsyc.56.1.78
Subject(s) - panic disorder , psychology , panic , anxiety , lateralization of brain function , electroencephalography , frontal lobe , anxiety disorder , audiology , neuroscience , psychiatry , medicine
Right frontal hemisphere activation, as indicated by reduced frontal alpha amplitude, seems to represent activation of an avoidance-withdrawal system and seems to be associated with negative emotions. Since patients with panic disorder are characterized by both negative emotions and avoidance-withdrawal behavior, we expected them to show greater right than left frontal hemisphere activation.

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