A Double-blind, Placebo-Controlled Study of Risperidone in Adults With Autistic Disorder and Other Pervasive Developmental Disorders | Zendy

Christopher J. McDougle | Zendy; Janice P. Holmes | Zendy; Derek C. Carlson | Zendy; Gregory H. Pelton | Zendy; Donald J. Cohen | Zendy; Lawrence H. Price | Zendy

Open Access

A Double-blind, Placebo-Controlled Study of Risperidone in Adults With Autistic Disorder and Other Pervasive Developmental Disorders

Author(s) -

Christopher J. McDougle,

Janice P. Holmes,

Derek C. Carlson,

Gregory H. Pelton,

Donald J. Cohen,

Lawrence H. Price

Publication year - 1998

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.55.7.633

Subject(s) - risperidone , autism , placebo , psychology , irritability , pervasive developmental disorder , psychiatry , extrapyramidal symptoms , anxiety , placebo controlled study , developmental disorder , medicine , double blind , schizophrenia (object oriented programming) , antipsychotic , alternative medicine , pathology

Neurobiological research has implicated the dopamine and serotonin systems in the pathogenesis of autism. Open-label reports suggest that the serotonin2A-dopamine D2 antagonist risperidone may be safe and effective in reducing the interfering symptoms of patients with autism.

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