First-Episode Schizophrenic Psychosis Differs From First-Episode Affective Psychosis and Controls in P300 Amplitude Over Left Temporal Lobe | Zendy

Dean F. Salisbury | Zendy; Martha E. Shenton | Zendy; Andrea R. Sherwood | Zendy; Iris A. Fischer | Zendy; Deborah YurgelunTodd | Zendy; Mauricio Tohen | Zendy; Robert W. McCarley | Zendy

Open Access

First-Episode Schizophrenic Psychosis Differs From First-Episode Affective Psychosis and Controls in P300 Amplitude Over Left Temporal Lobe

Author(s) -

Dean F. Salisbury,

Martha E. Shenton,

Andrea R. Sherwood,

Iris A. Fischer,

Deborah YurgelunTodd,

Mauricio Tohen,

Robert W. McCarley

Publication year - 1998

Publication title -

archives of general psychiatry

Language(s) - English

Resource type - Journals

eISSN - 1538-3636

pISSN - 0003-990X

DOI - 10.1001/archpsyc.55.2.173

Subject(s) - temporal lobe , psychosis , psychology , audiology , schizophrenia (object oriented programming) , abnormality , event related potential , superior temporal gyrus , neuroscience , psychiatry , cognition , medicine , epilepsy , functional magnetic resonance imaging

Schizophrenia is associated with central (sagittal) midline reductions of the P300 cognitive event-related potential and topographic asymmetry of P300, with reduced left temporal voltage. This P300 asymmetry is, in turn, linked to tissue volume asymmetry in the posterior superior temporal gyrus. However, it is unknown whether P300 asymmetry is specific to schizophrenia and whether central and lateral P300 abnormalities are due to chronic morbidity, neuroleptic medication, and/or hospitalization, or whether they are present at the onset of illness.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research